hi @matthewfeickert ! so, first i made sure that i have:

[Monday 04.04.22 19:14] adrian@ALICE2 : ~  $ 
python3 -m pip install --no-cache-dir --user --upgrade pip setuptools wheel
/usr/lib/python3/dist-packages/secretstorage/dhcrypto.py:15: CryptographyDeprecationWarning: int_from_bytes is deprecated, use int.from_bytes instead
  from cryptography.utils import int_from_bytes
/usr/lib/python3/dist-packages/secretstorage/util.py:19: CryptographyDeprecationWarning: int_from_bytes is deprecated, use int.from_bytes instead
  from cryptography.utils import int_from_bytes
Requirement already satisfied: pip in ./.local/lib/python3.8/site-packages (22.0.4)
Requirement already satisfied: setuptools in ./.local/lib/python3.8/site-packages (62.0.0)
Requirement already satisfied: wheel in ./.local/lib/python3.8/site-packages (0.37.1)

also

root@ALICE2:~# apt install -y python3 python3-dev python3-venv python3-pip
Reading package lists... Done
Building dependency tree       
Reading state information... Done
python3 is already the newest version (3.8.2-0ubuntu2).
python3 set to manually installed.
python3-dev is already the newest version (3.8.2-0ubuntu2).
python3-venv is already the newest version (3.8.2-0ubuntu2).
python3-pip is already the newest version (20.0.2-5ubuntu1.6)

so, answering by points:

1. so, would it means that on Debian derivatives, binary python packages are not functional unless one, after pip install --user modify by hand the environment?
   how the others (rhel/fedora) can make it work and cannot be replicated by the pip install process?
2. i see that i already answered above :)

Thanks a lot!

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