moreover setuptools 59.6.0 is the last one to work on python 3.6 so we will have to take into account different behaviors (depending on platform + python version) just skimming trough the list i see a lot of changes after 59.6.0 like:

@adriansev just to follow up on your good point, while this is correct (for installs from PyPI only — CMake builds from source are fine with any version of setuptools) this isn't so bad in terms of (more temporary) fixes.

If you simply just do

SETUPTOOLS_USE_DISTUTILS=stdlib python3 -m pip install --verbose 'xrootd==5.4.2'

then this will work right out of the box on Ubuntu for setuptools>60.0.0. So not bad for a temporary workaround 👍 — thank you for pointing that out!

Here's a Dockerfile showing that working without any LD_LIBRARY_PATH manipulation and (to really show that this would work for your current methods) even using pip install --user with no virtual environment.

Dockerfile for setuptools>60.0.0 on Ubuntu 20.04:
ARG BASE_IMAGE=ubuntu:20.04
FROM ${BASE_IMAGE} as base

SHELL [ "/bin/bash", "-c" ]

ENV PATH=/usr/local/venv/bin:"${PATH}"
RUN apt-get update && \
    DEBIAN_FRONTEND=noninteractive apt-get install -y --no-install-recommends \
        g++ \
        git \
        cmake \
        uuid-dev \
        dpkg-dev \
        libssl-dev \
        libx11-dev \
        libxml2-dev \
        libkrb5-dev \
        libgsl0-dev \
        pkg-config \
        tree \
        python3 \
        python3-pip \
        python3-venv \
        python3-dev && \
    apt-get autoclean -y && \
    python3 -m pip --no-cache-dir install --upgrade pip setuptools wheel && \
    python3 -m pip list

WORKDIR /
# Show --user even though I don't recommend it just to show it works
RUN python3 -m pip --no-cache-dir install --user --upgrade pip 'setuptools>60.0.0' wheel && \
    SETUPTOOLS_USE_DISTUTILS=stdlib python3 -m pip install --user --verbose 'xrootd==5.4.2' && \
    python3 -m pip list

RUN python3 -m pip list && \
    python3 -m pip show xrootd && \
    python3 -c 'import XRootD; print(XRootD)' && \
    python3 -c 'import pyxrootd; print(pyxrootd)' && \
    python3 -c 'from XRootD import client; print(client.FileSystem("root://someserver:1094"))'

WORKDIR /

CMD ["/bin/bash"]
docker build . -f Dockerfile -t xrootd/xrootd:issue-1668-setuptools-60-plus
$ docker run --rm -ti xrootd/xrootd:issue-1668-setuptools-60-plus
root@debb0c80d455:/# python3 -m pip show xrootd
Name: xrootd
Version: 5.4.2-
Summary: 
Home-page: 
Author: 
Author-email: 
License: 
Location: /root/.local/lib/python3.8/site-packages
Requires: 
Required-by: 
root@debb0c80d455:/# ls -lhtra /root/.local/lib/python3.8/site-packages
total 20K
drwxr-xr-x 3 root root 4.0K Apr  7 06:02 ..
drwxr-xr-x 2 root root 4.0K Apr  7 06:03 xrootd-5.4.2_.dist-info
drwxr-xr-x 6 root root 4.0K Apr  7 06:03 pyxrootd
drwxr-xr-x 4 root root 4.0K Apr  7 06:03 XRootD
drwx------ 5 root root 4.0K Apr  7 06:03 .
root@debb0c80d455:/# 


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